Reevaluating Golgi fragmentation and its implications in wound repair

Cell Regeneration

Table 1 Comparison of GA morphology and role in different cell types

Organism	*S. cerevisae*	*P. pastoris*	*C. elegans*	*N. tabacum*	*H. Sapiens*
Cell examined			Adult hyp7	BY-2	HT-29	SU.86.86	aRG	Myocytes	Myoblast
Cell Features	Mono-nuclear	Mono-nuclear	Multi-nucleated, Syncytium, Fully differentiated	Mono-nuclear	Mono-nuclear	Mono-nuclear	Mono-nuclear, stem cell	Multi-nucleated, fully differentiated	Mono-nuclear, stem cell
GA distribution	NP	NP	NP	NP+P	P	NP	NP+P	NP+P	P
GA Features	non-stacked, not divide during mitosis	stacked, not divide during mitosis, Generated from tER	stacked, matured	Stacked, preserved during mitosis.	Fragmented	Fragmented	Apical positioned	Fragmented	Stacked, ribbon like
Role	sorting station for both secretory and endocytic cargoes	Peroxisome function, Autophagosome formation	Promotes PM repair	Promotes cell wall and cell plate formation during cytokinesis	Promotes metastasis	Promotes metastasis	Controls bRG formation, Cell Polarity	Repair PM upon mechanical stress	Cell migration
References	Day et al. 2018; Suda and Nakano 2012	Manjithaya et al. 2010; Suda and Nakano 2012	Altun and Hall 2009; Meng et al. 2023; Zhu et al. 2016	Neumann et al. 2003; Rosquete et al. 2018	Bui et al. 2021; Kellokumpu et al. 2002; Petrosyan and Cheng 2013	Bui et al. 2021	Taverna et al. 2016; Xie et al. 2018	Quassollo et al. 2015; Ralston et al. 2001; Percival and Froehner 2007; Yadav et al. 2009	Percival and Froehner 2007; Yadav et al. 2009