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  1. Methodology

    Generation of knockout rabbits using transcription activator-like effector nucleases

    Zinc-finger nucleases and transcription activator-like effector nucleases are novel gene-editing platforms contributing to redefine the boundaries of modern biological research. They are composed of a non-spec...

    Yu Wang, Nana Fan, Jun Song, Juan Zhong, Xiaogang Guo, Weihua Tian, Quanjun Zhang, Fenggong Cui, Li Li, Philip N Newsome, Jon Frampton, Miguel A Esteban and Liangxue Lai

    Cell Regeneration 2014 3:3

    Published on: 5 February 2014

  2. Research

    Characterization of a novel cell penetrating peptide derived from human Oct4

    Oct4 is a transcription factor that plays a major role for the preservation of the pluripotent state in embryonic stem cells as well as for efficient reprogramming of somatic cells to induced pluripotent stem ...

    Eva Harreither, Hanna A Rydberg, Helene L Åmand, Vaibhav Jadhav, Lukas Fliedl, Christina Benda, Miguel A Esteban, Duanqing Pei, Nicole Borth, Regina Grillari-Voglauer, Oliver Hommerding, Frank Edenhofer, Bengt Nordén and Johannes Grillari

    Cell Regeneration 2014 3:2

    Published on: 31 January 2014

  3. Review

    Defining synthetic surfaces for human pluripotent stem cell culture

    Human pluripotent stem cells (hPSCs) are able to self-renew indefinitely and to differentiate into all adult cell types. hPSCs therefore show potential for application to drug screening, disease modelling and ...

    Jack W Lambshead, Laurence Meagher, Carmel O'Brien and Andrew L Laslett

    Cell Regeneration 2013 2:7

    Published on: 22 November 2013

  4. Research

    Generation of tooth-like structures from integration-free human urine induced pluripotent stem cells

    Tooth is vital not only for a good smile, but also good health. Yet, we lose tooth regularly due to accidents or diseases. An ideal solution to this problem is to regenerate tooth with patients’ own cells. Her...

    Jinglei Cai, Yanmei Zhang, Pengfei Liu, Shubin Chen, Xuan Wu, Yuhua Sun, Ang Li, Ke Huang, Rongping Luo, Lihui Wang, Ying Liu, Ting Zhou, Shicheng Wei, Guangjin Pan and Duanqing Pei

    Cell Regeneration 2013 2:6

    Published on: 30 July 2013

  5. Research

    SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells

    Sorting nexins are a large family of proteins that are associated with various components of the endosome system and they play many roles in processes such as endocytosis, intracellular protein trafficking and...

    Leilei Zhang, Dajiang Qin, Chunfang Hao, Xiaodong Shu and Duanqing Pei

    Cell Regeneration 2013 2:3

    Published on: 30 April 2013

  6. Research

    The involvement of interleukin-22 in the expression of pancreatic beta cell regenerative Reg genes

    In Type 1 diabetes, the insulin-producing β-cells within the pancreatic islets of Langerhans are destroyed. We showed previously that immunotherapy with Bacillus Calmette-Guerin (BCG) or complete Freund’s adju...

    Thomas Hill, Olga Krougly, Enayat Nikoopour, Stacey Bellemore, Edwin Lee-Chan, Lynette A Fouser, David J Hill and Bhagirath Singh

    Cell Regeneration 2013 2:2

    Published on: 4 April 2013

  7. Review

    Generation of functional organs from stem cells

    We are now well entering the exciting era of stem cells. Potential stem cell therapy holds great promise for the treatment of many diseases such as stroke, traumatic brain injury, Alzheimer’s disease, Parkinso...

    Yunying Liu, Ru Yang, Zuping He and Wei-Qiang Gao

    Cell Regeneration 2013 2:1

    Published on: 22 January 2013

  8. Review

    Return to the hematopoietic stem cell origin

    Studying embryonic hematopoiesis is complicated by diversity of its locations in the constantly changing anatomy and by the mobility of blood cell precursors. Embryonic hematopoietic progenitors are identified...

    Igor M Samokhvalov

    Cell Regeneration 2012 1:9

    Published on: 20 December 2012

  9. Review

    Pluripotency and its layers of complexity

    Pluripotency is depicted by a self-renewing state that can competently differentiate to form the three germ layers. Different stages of early murine development can be captured on a petri dish, delineating a s...

    Jolene Ooi and Pentao Liu

    Cell Regeneration 2012 1:7

    Published on: 14 September 2012

  10. Review

    Progress and bottleneck in induced pluripotency

    With their capability to undergo unlimited self-renewal and to differentiate into all cell types in the body, induced pluripotent stem cells (iPSCs), reprogrammed from somatic cells of individual patients with...

    Zhen-Ning Zhang and Yang Xu

    Cell Regeneration 2012 1:5

    Published on: 6 July 2012

  11. Short report

    Increased oxygen consumption and OXPHOS potential in superhealer mesenchymal stem cells

    Cell-based therapies show promise in repairing cardiac tissue and improving contractile performance following a myocardial infarction. Despite this, ischemia-induced death of transplanted cells remains a major...

    Curtis C Hughey, Maria P Alfaro, Darrell D Belke, Jeffery N Rottman, Pampee P Young, David H Wasserman and Jane Shearer

    Cell Regeneration 2012 1:3

    Published on: 28 June 2012

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