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Figure 5 | Cell Regeneration

Figure 5

From: Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors

Figure 5

Cancer versus Normal profile of Y-iPSCs and T-iPSCs aberrantly methylated regions. DNA methylation difference (delta beta value) between cancer patients and matched normal tissue of each CpG site identified as aberrantly methylated in Y-iPSCs (left panels) or T-iPSCs (right panels). The DNA methylation data was obtained from the TCGA depository (http://tcga-data.nci.nih.gov) for (A) Colon adenocarcinoma – COAD (258 tumor samples and 38 normal samples), (B) Head and neck squamous cell carcinoma – HNSC (310 tumor samples and 50 normal samples).

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