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Table 2 Gene ontology of genes associated with differentially methylated regions

From: Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors

iPS type GO Biological process P-value FDR Q-value Fold enrichment
Y-iPSCs Regulation of glial cell proliferation 5.72 × 10-13 5.01 × 10-9 8.2103
Y-iPSCs Intestinal epithelial cell differentiation 2.98 × 10-11 4.35 × 10-8 10.7333
Y-iPSCs Stem cell development 6.19 × 10-6 9.04 × 10-4 2.247
Y-iPSCs Stem cell maintenance 6.81 × 10-6 9.63 × 10-4 2.2958
T-iPSCs Eye development 3.81 × 10-11 6.68 × 10-8 6.5284
T-iPSCs Spinal cord development 3.68 × 10-9 3.58 × 10-6 2.4715
T-iPSCs Limb bud formation 6.50 × 10-6 1.09 × 10-3 3.1573
  1. GREAT tool [22] was used annotate genes with aberrant methylation in their transcription start site.