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Fig. 2 | Cell Regeneration

Fig. 2

From: RNA-binding proteins in mouse male germline stem cells: a mammalian perspective

Fig. 2

Mouse spermatogonial stem cells. Gonocytes (descendents of PGC in male embryonic gonad, also called prospermatonia) resume mitotic cell division and migrate from the center of growing seminiferous tubule to the basement membrane during the first 3 days following the birth of the animal. Spermatogonial stem cell (SSC) colonies are established around 7 dpp (days post-partum) at the inner surface of seminiferous tubule. They both undergo self-renewal to replenish stem cell pool and differentiation toward the lumen in order to generate sperm cells throughout the life of adult animal. RNA-binding proteins (depicted in the diagram) participate in the regulation of self-renewal and differentiation of SSCs

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