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Fig. 1 | Cell Regeneration

Fig. 1

From: Dissecting microRNA-mediated regulation of stemness, reprogramming, and pluripotency

Fig. 1

Functions of microRNAs (miRNAs) in embryonic stem cell (ESC) self-renewal, differentiation, and cellular reprogramming. ESC-specific miRNAs are involved in the maintenance and differentiation of ESCs by regulating key pluripotency factors (Oct4, Sox2, and Nanog), signaling molecules, and cell cycle distribution. Furthermore, these miRNAs play important roles in somatic cell reprogramming to gain pluripotency via epigenetic regulations

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